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5 February 2019 - Takis announces the publication of a paper exploring current antifungal therapeutic strategies

Takis is proud to announce the publication of the article "The Yin and Yang of Current Antifungal Therapeutic Strategies: How Can We Harness Our Natural Defenses?" by Di Mambro et al on Frontiers in Pharmacology.

Fungal infections are deadly diseases in immunocompromised hosts. Most importantly, fungi are becoming resistant to current treatments. Here, we summarize currently used antifungal agents and propose novel therapeutic approaches, including new fungal molecular targets to be considered for drug development.

Takis has an active program on the generation of monoclonal antibodies against Aspergillus Fumigatus and other species. We set up a rodent model of Invasive Aspergillosis, which is suitable for the evaluation of new drugs and combination with existing standard of care.

Full article available at: The Yin and Yang of Current Antifungal Therapeutic Strategies: How Can We Harness Our Natural Defenses?